Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CA3 | P07451 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.61 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30588914 | 1.00 | TDP1 (0.61) | TDP1CA12CA1CA9MCL1 | |
| SCHEMBL30450770 | 1.00 | TDP1 (0.61) | TDP1CA12CA1CA9MCL1 | |
| SCHEMBL31035850 | 0.98 | TDP1 (0.59) | TDP1CA12CA1CA9MCL1 | |
| SCHEMBL5672210 | 0.98 | TDP1 (0.59) | TDP1CA12CA1CA9MCL1 | |
| SCHEMBL5672676 | 0.87 | TDP1 (0.62) | TDP1CA12CA1CA9MCL1 | |
| Coumarin SCHEMBL28593553 | 0.79 | CA12 (0.95) | TDP1CA12CA1CA9MCL1 | |
| SCHEMBL5189602 | 0.78 | HPRT1 (0.54) | TDP1CA12CA1CA9MCL1 | |
| Xanthone SCHEMBL28056746 | 0.77 | TDP1 (0.74) | TDP1CA12CA1CA9MCL1 | |
| SCHEMBL7755371 | 0.77 | TDP1 (0.56) | TDP1CA12CA1CA9MCL1 | |
| Coumarin SCHEMBL28199186 | 0.77 | CA12 (0.67) | TDP1CA12CA1CA9MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116135848-A | Coumarin compound and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2023-05-19 | — | — | CN | claimed |
| EP-0869785-B1 | 4-HYDROXYCOUMARIN-3-CARBOXAMIDES FOR THE TREATMENT OF NON-INSULIN DEPENDENT DIABETES MELLITUS | UPJOHN CO (US) | 2002-08-28 | — | — | EP | claimed |
| JP-2000500490-A | — | — | 2000-01-18 | — | — | JP | claimed |
| EP-0869785-A1 | 4-HYDROXYCOUMARIN-3-CARBOXAMIDES FOR THE TREATMENT OF DIABETES MELLITUS | PHARMACIA & UPJOHN COMPANY (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1997018808-A1 | 4-HYDROXYCOUMARIN-3-CARBOXAMIDES FOR THE TREATMENT OF DIABETES MELLITUS | PHARMACIA & UPJOHN COMPANY (US) | 1997-05-29 | — | — | WO | claimed |
| EP-0605566-A1 | LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH | EASTMAN CHEMICAL COMPANY (US) | 1994-07-13 | — | — | EP | claimed |
| WO-1993006147-A1 | LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH | EASTMAN KODAK COMPANY (US) | 1993-04-01 | — | — | WO | claimed |
| US-5194463-A | LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH | EASTMAN KODAK COMPANY (US) | 1993-03-16 | — | — | US | claimed |
| JP-7252247-A | — | — | None | — | — | JP | disclosed |
| JP-7206858-A | — | — | None | — | — | JP | disclosed |
| US-12194003-B2 | Compositions for treating acne and dermatological conditions | Ilera Derm LLC (US) | 2025-01-14 | — | — | US | disclosed |
| US-20240130980-A1 | COMPOSITIONS FOR TREATING ACNE AND DERMATOLOGICAL CONDITIONS | Ilera Derm LLC | 2024-04-25 | — | — | US | disclosed |
| CN-116135848-B | Coumarin compound and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2024-03-12 | — | — | CN | disclosed |
| US-20240067620-A1 | COUMARIN GLYOXYLATES FOR LED PHOTOCURING | IGM RESINS ITALIA S.R.L. (IT) | 2024-02-29 | — | — | US | disclosed |
| US-4578469-A | COUMARIN DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-03-25 | — | — | US | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
| US-4281855-A | Pressure-sensitive or heat-sensitive recording material and novel 2,2-diarylchromeno compounds used therein | CIBA-GEIGY CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
| US-4187233-A | Pressure-sensitive or heat-sensitive recording material and novel 2,2-diarylchromeno compounds used therein | CIBA-GEIGY CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
| US-4177195-A | ORANGE AND YELLOW PIGMENTS FOR PAINTS, PLASTICS, AND INKS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-12-04 | — | — | US | disclosed |
| US-3966755-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067620-A1 | COUMARIN GLYOXYLATES FOR LED PHOTOCURING | AGXT, GRHPR, GLO1 | TDP1 4015/4885CA12 2376/4885CA1 2400/4885 |
| US-20240130980-A1 | COMPOSITIONS FOR TREATING ACNE AND DERMATOLOGICAL CONDITIONS | COQ8A, ATP5ME, AGK | TDP1 1945/4885CA12 4347/4885CA1 4837/4885 |
| US-12194003-B2 | Compositions for treating acne and dermatological conditions | COQ8A, ATP5ME, AGK | TDP1 1945/4885CA12 4347/4885CA1 4837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.