Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 8/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032801 | 1.00 | NAMPT (0.52) | NAMPTABL1NPC1RAB9ALMNA | |
| SCHEMBL29032719 | 0.87 | ABL1 (0.57) | ABL1LMNASMN1; SMN2 | |
| SCHEMBL30451175 | 0.87 | ABL1 (0.57) | ABL1LMNASMN1; SMN2 | |
| SCHEMBL29032784 | 0.85 | NAMPT (0.56) | NAMPTABL1NPC1RAB9ALMNA | |
| SCHEMBL30451056 | 0.85 | NAMPT (0.56) | NAMPTABL1NPC1RAB9ALMNA | |
| SCHEMBL30450644 | 0.83 | ABL1 (0.55) | ABL1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL29032789 | 0.83 | ABL1 (0.55) | ABL1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL29032794 | 0.83 | ABL1 (0.57) | ABL1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL29032704 | 0.81 | ABL1 (0.59) | ABL1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL30451563 | 0.80 | ABL1 (0.51) | ABL1NPC1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | disclosed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | disclosed |