Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.45 |
| ▸ | RHOC | P08134 | 2/20 | 0.45 |
| ▸ | RHOA | P61586 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23985109 | 0.90 | NR1H4 (0.51) | LMNAP2RX1RHOCRHOAPTGS1 | |
| SCHEMBL23985155 | 0.79 | KCNK3 (0.58) | LMNAP2RX1RHOCRHOAPTGS1 | |
| SCHEMBL23985152 | 0.78 | RHOC (0.60) | LMNAP2RX1RHOCRHOAPTGS1 | |
| SCHEMBL30554615 | 0.73 | P2RX1 (0.65) | P2RX1RHOCRHOAMAPTRXFP1 | |
| SCHEMBL3246188 | 0.73 | P2RX1 (0.65) | P2RX1RHOCRHOAMAPTRXFP1 | |
| SCHEMBL678377 | 0.72 | PTGS1 (0.68) | LMNAP2RX1RHOCRHOAPTGS1 | |
| Hydrochloric Acid SCHEMBL30481169 | 0.71 | EPHX1 (0.44) | MAPTMEN1KMT2A | |
| SCHEMBL22772371 | 0.71 | ABL1 (0.57) | LMNAP2RX1RHOCRHOAPTGS1 | |
| SCHEMBL5389064 | 0.70 | RXRA (0.49) | — | |
| SCHEMBL14528862 | 0.69 | RHOC (0.48) | RHOCRHOAHDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261562-A | PI 3K-alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-06-13 | — | — | CN | disclosed |