Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15910226 | 1.00 | KIF11 (0.58) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL15910239 | 0.93 | KIF11 (0.72) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL22907728 | 0.92 | KIF11 (0.50) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL22514643 | 0.91 | KIF11 (0.65) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL24125950 | 0.88 | KIF11 (0.53) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL262474 | 0.88 | KIF11 (0.53) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL31567515 | 0.88 | KIF11 (0.44) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL15770211 | 0.87 | KIF11 (0.54) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL20100119 | 0.86 | KCNH2 (0.42) | KIF11HTR1DKCNH2MEN1KMT2A | |
| SCHEMBL23050967 | 0.84 | KIF11 (0.68) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159457-A1 | FLUORENE DERIVATIVES, POLYMERS OBTAINED FROM SAID FLUORENE DERIVATIVES AND METHOD FOR PREPARING THE SAME | IRPC PUBLIC COMPANY LIMITED (TH) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159457-A1 | FLUORENE DERIVATIVES, POLYMERS OBTAINED FROM SAID FLUORENE DERIVATIVES AND METHOD FOR PREPARING THE SAME | TERT, F12, F3 | KIF11 2069/4885GABRA1 1959/4885GABRG2 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.