Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | GMNN | O75496 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18004108 | 1.00 | SCN4A (0.70) | SCN4AEPHX2RAB9ANPC1TP53 | |
| SCHEMBL20568080 | 0.86 | RAB9A (0.84) | SCN4AEPHX2RAB9ANPC1TP53 | |
| SCHEMBL25257398 | 0.84 | SCN4A (0.60) | SCN4AEPHX2RAB9ANPC1TP53 | |
| SCHEMBL30450378 | 0.84 | SCN4A (0.60) | SCN4AEPHX2RAB9ANPC1TP53 | |
| SCHEMBL6067934 | 0.84 | RAB9A (0.75) | SCN4AEPHX2RAB9ANPC1TP53 | |
| SCHEMBL31114514 | 0.84 | RAB9A (0.75) | SCN4ARAB9ANPC1TP53SMN1; SMN2 | |
| SCHEMBL25306149 | 0.84 | RAB9A (0.75) | SCN4ARAB9ANPC1TP53SMN1; SMN2 | |
| SCHEMBL31114771 | 0.84 | RAB9A (0.75) | SCN4AEPHX2RAB9ANPC1TP53 | |
| SCHEMBL10694424 | 0.83 | SCN4A (0.63) | SCN4AEPHX2RAB9ANPC1TP53 | |
| SCHEMBL1417399 | 0.83 | SCN4A (1.00) | SCN4AEPHX2RAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4460500-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2024-11-13 | — | — | EP | disclosed |
| CN-118660885-A | Norbornene analogs and their use as potentiators of antitubercular drugs | 国家医疗保健研究所 | 2024-09-17 | — | — | CN | disclosed |
| WO-2023131649-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-07-13 | — | — | WO | disclosed |