Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29141888 | 0.93 | MAPT (0.43) | THRBALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL11266840 | 0.88 | THRB (0.47) | THRBALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL11261814 | 0.86 | MAPT (0.46) | THRBALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL11141400 | 0.84 | HTR2A (0.45) | THRBALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL30450291 | 0.82 | LMNA (0.48) | NPSR1MAOBMAPTMEN1KMT2A | |
| SCHEMBL11294373 | 0.81 | MAPT (0.48) | THRBALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL11292203 | 0.81 | MAPT (0.48) | THRBALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| Hydrochloric Acid SCHEMBL25400192 | 0.80 | KMT2A (0.41) | THRBALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL11295197 | 0.80 | MAPT (0.50) | THRBALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL11292125 | 0.80 | MAPT (0.50) | THRBALDH1A1SMN1; SMN2KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894195-A | Method for preparing 1-aryl-3-substituted acetone compound and intermediate | 迈克斯(如东)化工有限公司 | 2023-04-04 | — | — | CN | disclosed |