Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22122731 | 1.00 | PYCR1 (0.42) | PYCR1ALOX15ALOX12PPARAEPHX1 | |
| SCHEMBL22145313 | 0.86 | PYCR1 (0.44) | PYCR1ALOX15ALOX12PPARAEPHX1 | |
| SCHEMBL22122785 | 0.86 | PYCR1 (0.44) | PYCR1ALOX15ALOX12PPARAEPHX1 | |
| SCHEMBL30485975 | 0.86 | PYCR1 (0.44) | PYCR1ALOX15ALOX12PPARAEPHX1 | |
| SCHEMBL22122732 | 0.84 | ALOX15 (0.46) | PYCR1ALOX15ALOX12PPARAEPHX1 | |
| SCHEMBL22122759 | 0.83 | PYCR1 (0.39) | PYCR1ALOX15ALOX12PPARAPPARG | |
| SCHEMBL15083013 | 0.82 | EPHX1 (0.48) | ALOX15ALOX12EPHX1MEN1KMT2A | |
| SCHEMBL22125042 | 0.82 | PYCR1 (0.46) | PYCR1ALOX15ALOX12PPARAPPARG | |
| SCHEMBL22122730 | 0.79 | PYCR1 (0.42) | PYCR1ALOX15ALOX12PPARAPPARG | |
| SCHEMBL22162895 | 0.79 | PYCR1 (0.42) | PYCR1ALOX15ALOX12PPARAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |