Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 3/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28336783 | 0.79 | CES1 (0.37) | KMT2APOLBMEN1GAAMAPK1 | |
| SCHEMBL9053384 | 0.74 | KMT2A (0.86) | KMT2APOLBMEN1GAAMAPK1 | |
| SCHEMBL29963082 | 0.74 | KMT2A (0.86) | KMT2APOLBMEN1GAAMAPK1 | |
| SCHEMBL29622070 | 0.72 | TNKS (0.49) | AKR1B1CES1PDE7ATGM2NSD2 | |
| SCHEMBL17556137 | 0.72 | TNKS (0.49) | AKR1B1CES1PDE7ATGM2NSD2 | |
| SCHEMBL24112426 | 0.69 | PDK2 (0.53) | AKR1B1CES1PDE7ATGM2PBRM1 | |
| SCHEMBL31332564 | 0.69 | CES1 (0.46) | AKR1B1CES1PDE7ATGM2PBRM1 | |
| SCHEMBL16687077 | 0.69 | PGR (0.50) | AKR1B1CES1PDE7AAHRTNKS2 | |
| SCHEMBL5225323 | 0.68 | PGR (0.65) | KMT2APOLBMEN1 | |
| SCHEMBL29963500 | 0.68 | GAA (1.00) | KMT2APOLBMEN1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563631-B | IDO inhibiting compound and application thereof | 爱斯特（成都）生物制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |