SCHEMBL30452252

SCHEMBL30452252

Fc1cccc(Sc2cccc(F)c2F)c1F

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.42
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41
BCHE P06276 1/20 0.41
PTGS2 P35354 1/20 0.40
HAO1 Q9UJM8 1/20 0.35
CXCR2 P25025 2/20 0.33
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 1/20 0.32
ACHE P22303 1/20 0.32
HPGD P15428 1/20 0.31
NFE2L2 Q16236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL576234 1.00 NOTUM (0.42) NOTUMCES2CES1BCHEPTGS2
SCHEMBL29722923 0.84 MAPT (0.44) NOTUMPTGS2HPGD
SCHEMBL776750 0.84 MAPT (0.44) NOTUMPTGS2HPGD
SCHEMBL576030 0.83 CES2 (0.41) NOTUMCES2CES1BCHEPTGS2
SCHEMBL30452870 0.83 CES2 (0.41) NOTUMCES2CES1BCHEPTGS2
SCHEMBL29722828 0.79 CES2 (0.38) NOTUMCES2CES1BCHEPTGS2
SCHEMBL775593 0.79 CES2 (0.38) NOTUMCES2CES1BCHEPTGS2
SCHEMBL2699555 0.79 CES2 (0.38) NOTUMCES2CES1BCHEPTGS2
SCHEMBL6873080 0.79 CES2 (0.38) NOTUMCES2CES1BCHEPTGS2
SCHEMBL575956 0.77 HAO1 (0.52) NOTUMCES2CES1PTGS2HAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115911573-A Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same 三菱化学株式会社 2023-04-04 CN disclosed