SCHEMBL30452870

SCHEMBL30452870

Fc1cccc(SSc2cccc(F)c2F)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41
BCHE P06276 1/20 0.41
APOBEC3G Q9HC16 2/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
NOTUM Q6P988 1/20 0.36
CXCR2 P25025 2/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
ACHE P22303 1/20 0.32
HPGD P15428 1/20 0.31
HAO1 Q9UJM8 1/20 0.31
PTGS2 P35354 1/20 0.31
POLB P06746 1/20 0.31
NFE2L2 Q16236 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL576030 1.00 CES2 (0.41) CES2CES1BCHEAPOBEC3GMEN1
SCHEMBL29722735 0.87 MAPT (0.50) CES2CES1BCHEAPOBEC3GMEN1
SCHEMBL775909 0.87 MAPT (0.50) CES2CES1BCHEAPOBEC3GMEN1
SCHEMBL29723042 0.85 CES2 (0.35) CES2CES1BCHENOTUMCXCR2
SCHEMBL776548 0.85 CES2 (0.35) CES2CES1BCHENOTUMCXCR2
SCHEMBL576234 0.83 NOTUM (0.42) CES2CES1BCHENOTUMCXCR2
SCHEMBL30452252 0.83 NOTUM (0.42) CES2CES1BCHENOTUMCXCR2
SCHEMBL778358 0.80 CXCR2 (0.36) CES2CES1BCHENOTUMCXCR2
SCHEMBL29722866 0.80 CXCR2 (0.36) CES2CES1BCHENOTUMCXCR2
SCHEMBL2699555 0.79 CES2 (0.38) CES2CES1BCHENOTUMCXCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115911573-A Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same 三菱化学株式会社 2023-04-04 CN disclosed