Sugi Predict

Sugi Predict / Compounds / SCHEMBL30452270

SCHEMBL30452270

SCHEMBL30452270

OC12CC3CC(C1)CC2(O)C3

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 1/20 0.42
▸ GRIN2D O15399 4/20 0.37
▸ GRIN3B O60391 4/20 0.37
▸ GRIN1 Q05586 4/20 0.37
▸ GRIN2A Q12879 4/20 0.37
▸ GRIN2B Q13224 4/20 0.37
▸ GRIN2C Q14957 4/20 0.37
▸ GRIN3A Q8TCU5 4/20 0.37
▸ LMNA P02545 3/20 0.37
▸ SLC22A2 O15244 1/20 0.37
▸ SLC22A1 O15245 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ NFKB1 P19838 1/20 0.37
▸ STAT6 P42226 1/20 0.37
▸ SLC47A1 Q96FL8 1/20 0.37
▸ SIGMAR1 Q99720 1/20 0.37
▸ SMN1; SMN2 Q16637 3/20 0.35
▸ POLB P06746 1/20 0.35
▸ THRB P10828 1/20 0.35
▸ BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27225513 0.86 PKM (0.39) PKMGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL24173315 0.78 PKM (0.44) PKMGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6854392 0.74 PKM (0.32) PKM
SCHEMBL28211287 0.74 PKM (0.32) PKM
Ammonia Solution, Strong SCHEMBL343273 0.73 PKM (0.31) PKM
SCHEMBL546365 0.72 GRIN2D (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL15858211 0.72 PKM (0.64) PKMALDH1A1HSD11B1
SCHEMBL424418 0.72 PKM (0.64) PKMALDH1A1HSD11B1
SCHEMBL1150706 0.72 PKM (0.64) PKMALDH1A1HSD11B1
SCHEMBL15467155 0.72 PKM (0.64) PKMALDH1A1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF ANNEXON INC (US) 2026-03-12 — — US disclosed
US-12509474-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2025-12-30 — — US disclosed
US-20240109920-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF ANNEXON, INC. 2024-04-04 — — US disclosed
US-11814404-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2023-11-14 — — US disclosed
CN-116947903-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-10-27 — — CN disclosed
CN-116261564-A Inhibitors of complement factors and uses thereof 安尼艾克松股份有限公司 2023-06-13 — — CN disclosed
EP-4185592-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF Annexon, Inc. (US) 2023-05-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109920-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF CFB, CFH, C9 PKM 2442/4885GRIN2D 2347/4885GRIN3B 715/4885
US-11814404-B2 Inhibitors of complement factors and uses thereof CFB, CFH, C9 PKM 2442/4885GRIN2D 2347/4885GRIN3B 715/4885
US-12509474-B2 Inhibitors of complement factors and uses thereof SSB, UACA, CFH PKM 4045/4885GRIN2D 2565/4885GRIN3B 1011/4885
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF CFH, CFB, C5 PKM 4234/4885GRIN2D 1221/4885GRIN3B 1054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.