Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.33 |
| ▸ | NAT1 | P18440 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096121 | 0.82 | PTPRC (0.46) | ESR2PTPN5PTPRCGABRG2GABRB3 | |
| SCHEMBL1461948 | 0.82 | ESR2 (0.52) | ESR2ADORA2AADORA1PTPN5GABRG2 | |
| SCHEMBL30869964 | 0.75 | MEN1 (0.42) | ESR2ADORA2AADORA1PTPRCTSHR | |
| SCHEMBL7266916 | 0.74 | IMPDH2 (0.39) | PTPRCIMPDH2TSHR | |
| SCHEMBL29412287 | 0.70 | ESR2 (0.60) | ESR2PTPN5GABRG2GABRB3GABRA5 | |
| SCHEMBL222 | 0.70 | ESR2 (0.60) | ESR2PTPN5GABRG2GABRB3GABRA5 | |
| Hydrochloric Acid SCHEMBL29998667 | 0.69 | LRRK2 (0.37) | ESR2ADORA2AADORA1IMPDH2DPP4 | |
| SCHEMBL30453765 | 0.69 | MEN1 (0.41) | ESR2ADORA2AADORA1PTPRCTSHR | |
| SCHEMBL31358675 | 0.64 | CHRM2 (0.42) | ADORA2AADORA1TSHRLRRK2 | |
| SCHEMBL12276361 | 0.64 | RIPK3 (0.38) | ADORA2AADORA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073401-B | 2,3 '-bisfuran compound, 2,3' -oligomeric furan compound, and preparation methods and applications thereof | 华南理工大学 | 2023-07-14 | — | — | CN | disclosed |