Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | USP8 | P40818 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30453765 | 0.84 | MEN1 (0.41) | PTPRCESR2TSHR | |
| SCHEMBL30869964 | 0.84 | MEN1 (0.42) | PTPRCESR2TSHR | |
| SCHEMBL30452328 | 0.82 | ESR2 (0.39) | PTPRCESR2TSHRPTPN5GABRG2 | |
| SCHEMBL222 | 0.78 | ESR2 (0.60) | ESR2TSHRPTPN5USP8USP7 | |
| SCHEMBL29412287 | 0.78 | ESR2 (0.60) | ESR2TSHRPTPN5USP8USP7 | |
| SCHEMBL12679722 | 0.73 | ESR2 (0.50) | ESR2TSHRPTPN5USP8USP7 | |
| SCHEMBL8476284 | 0.71 | MEN1 (0.50) | ESR2TSHRLMNA | |
| SCHEMBL31264118 | 0.71 | MEN1 (0.50) | ESR2TSHRLMNA | |
| Bicarbonate SCHEMBL7256331 | 0.69 | ESR2 (0.55) | ESR2TSHRPTPN5USP8USP7 | |
| SCHEMBL31358675 | 0.68 | CHRM2 (0.42) | TSHRCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020488-A | Small molecule inhibition of RNA/ligand binding | SCRIPTGEN PHARMACEUTICALS INC. (US) | 2000-02-01 | — | — | US | disclosed |
| US-5935776-A | 2,5-BIS(4-(3-N,N,-DIMETHYLAMINOPROPYLAMIDINO)PHENYL)FURAN OR PHARMACEUTICALLY ACCEPTABLE SALT AND DILUENT OR CARRIER AS VIRICIDE TO SUPPRESS BINDING OF REV PROTEIN TO MESSENGER RNAS THUS SUPPRESSING REPLICATION OF HUMAN IMMUNODEFICIENCY VIRUS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0833824-A2 | SMALL MOLECULE INHIBITION OF RNA/LIGAND BINDING | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1998-04-08 | — | — | EP | disclosed |
| US-5668165-A | TREATMENT OF HIV INFECTIONS | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1997-09-16 | — | — | US | disclosed |
| WO-1996040668-A2 | SMALL MOLECULE INHIBITION OF RNA/LIGAND BINDING | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |