Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252895 | 1.00 | DRD4 (0.47) | DRD4PTGER1NPC1HPGDALDH1A1 | |
| SCHEMBL30452003 | 0.86 | ALDH1A1 (0.49) | NPC1HPGDALDH1A1RAB9ALMNA | |
| SCHEMBL24252925 | 0.86 | ALDH1A1 (0.49) | NPC1HPGDALDH1A1RAB9ALMNA | |
| SCHEMBL15260164 | 0.83 | ALDH1A1 (0.43) | DRD4NPC1HPGDALDH1A1RAB9A | |
| SCHEMBL1197051 | 0.82 | PTGER1 (0.46) | DRD4PTGER1NPC1HPGDALDH1A1 | |
| SCHEMBL1505058 | 0.82 | PTGER1 (0.57) | DRD4PTGER1NPC1HPGDALDH1A1 | |
| SCHEMBL1197111 | 0.81 | PTGER1 (0.45) | DRD4PTGER1NPC1HPGDALDH1A1 | |
| SCHEMBL18585229 | 0.81 | MAPT (0.48) | DRD4PTGER1NPC1HPGDALDH1A1 | |
| SCHEMBL1926867 | 0.81 | RAB9A (0.47) | DRD4NPC1HPGDALDH1A1RAB9A | |
| SCHEMBL15260163 | 0.78 | DRD4 (0.47) | DRD4HPGDALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-4185592-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | Annexon, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |