Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257690 | 1.00 | CNR1 (0.39) | CNR1NQO1CSF1RMAOBGRM2 | |
| SCHEMBL24257718 | 0.89 | SMN1; SMN2 (0.39) | CNR1PDE10A | |
| SCHEMBL30452995 | 0.89 | SMN1; SMN2 (0.39) | CNR1PDE10A | |
| SCHEMBL30453400 | 0.88 | NPC1 (0.41) | CNR1CSF1R | |
| SCHEMBL24257586 | 0.88 | NPC1 (0.41) | CNR1CSF1R | |
| SCHEMBL24257729 | 0.85 | CYP11B1 (0.43) | CNR1GRM2PDE2A | |
| SCHEMBL30453284 | 0.85 | CYP11B1 (0.43) | CNR1GRM2PDE2A | |
| SCHEMBL30546865 | 0.82 | MAOB (0.43) | MAOBGRM2PDE10A | |
| Nitrous Acid SCHEMBL29248892 | 0.80 | MAOB (0.41) | MAOBGRM2PDE10A | |
| SCHEMBL24257819 | 0.79 | HSD17B10 (0.43) | CNR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196466-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2023-06-21 | — | — | EP | disclosed |