Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.68 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.46 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488550 | 1.00 | MET (0.68) | METBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL30453107 | 0.96 | MET (0.62) | METBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL488608 | 0.96 | MET (0.62) | METBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL30452884 | 0.94 | MET (0.59) | METNEK2CD274 | |
| SCHEMBL488139 | 0.94 | MET (0.59) | METNEK2CD274 | |
| SCHEMBL488486 | 0.89 | MET (0.54) | METNEK2CD274 | |
| SCHEMBL30453390 | 0.89 | MET (0.54) | METNEK2CD274 | |
| SCHEMBL30452899 | 0.84 | MET (0.48) | METBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL488715 | 0.84 | MET (0.48) | METBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL27630301 | 0.84 | MET (0.47) | METNEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |