Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.59 |
| ▸ | CD274 | Q9NZQ7 | 12/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NEK2 | P51955 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488139 | 1.00 | MET (0.59) | METCD274HPGDNEK2PDE4B | |
| SCHEMBL488486 | 0.96 | MET (0.54) | METCD274NEK2ALK | |
| SCHEMBL30453390 | 0.96 | MET (0.54) | METCD274NEK2ALK | |
| SCHEMBL30452449 | 0.94 | MET (0.68) | METCD274NEK2 | |
| SCHEMBL488550 | 0.94 | MET (0.68) | METCD274NEK2 | |
| SCHEMBL30453107 | 0.89 | MET (0.62) | METNEK2 | |
| SCHEMBL488608 | 0.89 | MET (0.62) | METNEK2 | |
| SCHEMBL5482536 | 0.85 | CD274 (0.53) | METCD274HPGDPDE4BHPGDS | |
| SCHEMBL30452523 | 0.83 | MET (0.71) | METCD274HPGDHPGDSALK | |
| SCHEMBL488275 | 0.83 | MET (0.71) | METCD274HPGDHPGDSALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |