Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | PPID | Q08752 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | VEGFA | P15692 | 3/20 | 0.41 |
| ▸ | FLT1 | P17948 | 3/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546822 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4ERXFP1SMN1; SMN2NCOA1 | |
| SCHEMBL24257545 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4ERXFP1SMN1; SMN2NCOA1 | |
| SCHEMBL30453195 | 0.89 | CASP1 (0.49) | ALDH1A1SMN1; SMN2PPIDCASP1EGLN3 | |
| SCHEMBL24257534 | 0.89 | CASP1 (0.49) | ALDH1A1SMN1; SMN2PPIDCASP1EGLN3 | |
| SCHEMBL30546862 | 0.86 | EGLN3 (0.55) | EGLN3VEGFAFLT1EGLN1 | |
| SCHEMBL24257682 | 0.86 | EGLN3 (0.55) | EGLN3VEGFAFLT1EGLN1 | |
| SCHEMBL24257568 | 0.84 | EGLN1 (0.58) | PPIDCASP1EGLN3VEGFAFLT1 | |
| SCHEMBL24257693 | 0.84 | EGLN1 (0.51) | ALDH1A1KDM4EPPIDEGLN3LMNA | |
| SCHEMBL24257789 | 0.84 | PPID (0.42) | SMN1; SMN2PPIDCASP1EGLN3VEGFA | |
| SCHEMBL30452447 | 0.84 | PPID (0.42) | SMN1; SMN2PPIDCASP1EGLN3VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295110-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | AKEBIA THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | US | disclosed |
| EP-4196466-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2023-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295110-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | HIF1AN, EGLN3, PHF20 | ALDH1A1 1362/4885KDM4E 175/4885RXFP1 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.