Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28431647 | 1.00 | TDO2 (0.37) | TDO2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL23957654 | 0.80 | GBA1 (0.39) | ALDH1A1NPC1RAB9ARXFP1EGLN1 | |
| SCHEMBL23929898 | 0.79 | GBA1 (0.35) | EGLN1GBA1 | |
| SCHEMBL23929900 | 0.79 | GBA1 (0.35) | EGLN1GBA1 | |
| SCHEMBL23930242 | 0.79 | GBA1 (0.50) | ALDH1A1NPC1RAB9ARXFP1EGLN1 | |
| SCHEMBL28938115 | 0.79 | TDO2 (0.37) | TDO2EGLN1GRM5 | |
| SCHEMBL31435193 | 0.79 | HCAR2 (0.39) | TDO2EGLN1GRM5GAA | |
| SCHEMBL28987739 | 0.79 | PRKCI (0.38) | ALDH1A1EGLN1HPGDTSHRHTT | |
| SCHEMBL23501178 | 0.76 | KCNJ1 (0.54) | TDO2ALDH1A1EGLN1GRM5KDM4E | |
| SCHEMBL22510981 | 0.76 | EGLN1 (0.42) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484479-B | Azacyclic compounds, pharmaceutical compositions containing the same, and methods of making and using the same | 四川科伦博泰生物医药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |