Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHB | P07195 | 9/20 | 0.55 |
| ▸ | LDHA | P00338 | 9/20 | 0.55 |
| ▸ | MET | P08581 | 5/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.53 |
| ▸ | ATR | Q13535 | 3/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488599 | 1.00 | LDHB (0.55) | LDHBLDHAMETCHEK2ATR | |
| SCHEMBL30452717 | 0.91 | MET (0.60) | LDHBLDHAMETCHEK2ATR | |
| SCHEMBL488702 | 0.91 | MET (0.60) | LDHBLDHAMETCHEK2ATR | |
| SCHEMBL30453109 | 0.90 | MET (0.58) | LDHBLDHAMETMAP4K3 | |
| SCHEMBL488216 | 0.90 | MET (0.58) | LDHBLDHAMETMAP4K3 | |
| SCHEMBL488504 | 0.87 | LDHB (0.53) | LDHBLDHAMETCHEK2ATR | |
| SCHEMBL30453484 | 0.87 | LDHB (0.53) | LDHBLDHAMETCHEK2ATR | |
| SCHEMBL10381108 | 0.85 | MET (0.55) | LDHBLDHAMETCHEK2ATR | |
| SCHEMBL489049 | 0.84 | ATR (0.55) | METCHEK2ATR | |
| SCHEMBL30453261 | 0.84 | ATR (0.55) | METCHEK2ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |