Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.40 |
| ▸ | MTOR | P42345 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.37 |
| ▸ | LGMN | Q99538 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257511 | 1.00 | SLC34A1 (0.40) | SLC34A1MTORPIK3CAMAP4K4KCNH2 | |
| SCHEMBL24257763 | 0.82 | KDM4E (0.35) | PDE10A | |
| SCHEMBL30546870 | 0.82 | KDM4E (0.35) | PDE10A | |
| SCHEMBL30452657 | 0.76 | PDE10A (0.39) | MTORPDE10A | |
| SCHEMBL24257740 | 0.76 | PDE10A (0.39) | MTORPDE10A | |
| SCHEMBL24257730 | 0.75 | NPSR1 (0.41) | MTORMAP4K4KCNH2 | |
| SCHEMBL30453225 | 0.75 | NPSR1 (0.41) | MTORMAP4K4KCNH2 | |
| SCHEMBL24257513 | 0.75 | KDM4E (0.38) | PDE10A | |
| SCHEMBL30453043 | 0.75 | KDM4E (0.38) | PDE10A | |
| SCHEMBL30546856 | 0.74 | PDE10A (0.38) | MTORPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670131-A | PHD inhibitor compounds, compositions, and methods of use | 阿克比治疗有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4196466-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2023-06-21 | — | — | EP | disclosed |