Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.64 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487818 | 1.00 | MET (0.64) | METMAP4K4MAP4K3ERN1CTSA | |
| SCHEMBL30453540 | 0.87 | MET (0.72) | METMAP4K4MAP4K3JAK2 | |
| SCHEMBL487624 | 0.87 | MET (0.72) | METMAP4K4MAP4K3JAK2 | |
| SCHEMBL487907 | 0.83 | MET (0.81) | METMAP4K4MAP4K3JAK2 | |
| SCHEMBL487962 | 0.82 | MET (0.62) | METMAP4K4MAP4K3MGAMGAA | |
| SCHEMBL488145 | 0.82 | MET (0.68) | METMAP4K4MAP4K3JAK2 | |
| SCHEMBL487619 | 0.82 | MET (0.71) | METMAP4K4MAP4K3JAK2 | |
| SCHEMBL488042 | 0.82 | MET (0.79) | METMAP4K4MAP4K3JAK2 | |
| SCHEMBL30452558 | 0.82 | MET (0.71) | METMAP4K4MAP4K3JAK2 | |
| Water SCHEMBL28121971 | 0.81 | MET (0.79) | METMAP4K4MAP4K3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |