Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.72 |
| ▸ | JAK2 | O60674 | 3/20 | 0.48 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487624 | 1.00 | MET (0.72) | METJAK2MAP4K3FYNMAP4K4 | |
| SCHEMBL487619 | 0.88 | MET (0.71) | METJAK2MAP4K3FYNMAP4K4 | |
| SCHEMBL30452558 | 0.88 | MET (0.71) | METJAK2MAP4K3FYNMAP4K4 | |
| SCHEMBL488042 | 0.88 | MET (0.79) | METJAK2MAP4K3FYNMAP4K4 | |
| SCHEMBL30452684 | 0.87 | MET (0.64) | METJAK2MAP4K3MAP4K4 | |
| SCHEMBL487818 | 0.87 | MET (0.64) | METJAK2MAP4K3MAP4K4 | |
| SCHEMBL487777 | 0.85 | MET (0.83) | METJAK2MAP4K3FYNMAP4K4 | |
| SCHEMBL488258 | 0.84 | MET (0.77) | METJAK2MAP4K3MAP4K4MPO | |
| SCHEMBL487830 | 0.84 | MET (1.00) | METMAP4K3FYNMAP4K4MPO | |
| SCHEMBL487572 | 0.84 | MET (0.73) | METJAK2MAP4K3FYNMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |