Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.57 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487968 | 1.00 | MET (0.57) | METCD274MKNK1MKNK2HPGD | |
| SCHEMBL487760 | 0.95 | MET (0.58) | METCD274HPGDHPGDS | |
| SCHEMBL488059 | 0.89 | MET (0.55) | METCD274HPGDKDM4EALDH1A1 | |
| SCHEMBL30454410 | 0.89 | MET (0.55) | METCD274HPGDKDM4EALDH1A1 | |
| SCHEMBL30453951 | 0.87 | MET (0.56) | METCD274HPGDKDM4EALDH1A1 | |
| SCHEMBL488455 | 0.87 | MET (0.56) | METCD274HPGDKDM4EALDH1A1 | |
| SCHEMBL30452829 | 0.84 | MET (0.56) | METCD274HPGDALDH1A1HPGDS | |
| SCHEMBL487776 | 0.84 | MET (0.56) | METCD274HPGDALDH1A1HPGDS | |
| SCHEMBL488220 | 0.84 | MET (0.55) | METCD274ALDH1A1SMN1; SMN2 | |
| SCHEMBL30453420 | 0.84 | MET (0.55) | METCD274ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |