Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.58 |
| ▸ | JAK2 | O60674 | 3/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487584 | 1.00 | MET (0.58) | METJAK2CSNK2BCSNK2A1PIK3CD | |
| SCHEMBL30453292 | 0.96 | MET (0.54) | METJAK2CSNK2BCSNK2A1PIK3CD | |
| SCHEMBL487645 | 0.96 | MET (0.54) | METJAK2CSNK2BCSNK2A1PIK3CD | |
| SCHEMBL30454885 | 0.87 | MET (0.42) | METJAK2CSNK2BCSNK2A1PIK3CD | |
| SCHEMBL487593 | 0.87 | MET (0.42) | METJAK2CSNK2BCSNK2A1PIK3CD | |
| SCHEMBL6361398 | 0.81 | MET (0.69) | METJAK2MPOUSP7MAP4K3 | |
| SCHEMBL487767 | 0.80 | MET (0.65) | METPIK3CDMPO | |
| SCHEMBL487729 | 0.78 | MET (0.65) | METJAK2MPOUSP7MAP4K3 | |
| SCHEMBL488040 | 0.78 | MET (0.65) | METJAK2PIK3CDPIK3CBMPO | |
| SCHEMBL487522 | 0.78 | MET (0.72) | METJAK2MPOUSP7MAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |