Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 3/20 | 0.39 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.37 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.37 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487593 | 1.00 | MET (0.42) | METJAK2ATRPIK3CDPIK3CB | |
| SCHEMBL487584 | 0.87 | MET (0.58) | METJAK2ATRPIK3CDPIK3CB | |
| SCHEMBL30452748 | 0.87 | MET (0.58) | METJAK2ATRPIK3CDPIK3CB | |
| SCHEMBL487645 | 0.85 | MET (0.54) | METJAK2ATRPIK3CDPIK3CB | |
| SCHEMBL30453292 | 0.85 | MET (0.54) | METJAK2ATRPIK3CDPIK3CB | |
| SCHEMBL487796 | 0.76 | MET (0.57) | METJAK2MAP4K3 | |
| Water SCHEMBL28122580 | 0.75 | MET (0.56) | METJAK2MAP4K3 | |
| SCHEMBL30452529 | 0.74 | MET (0.73) | MET | |
| SCHEMBL487592 | 0.74 | MET (0.73) | MET | |
| SCHEMBL487729 | 0.74 | MET (0.65) | METJAK2MAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |