Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 8/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.37 |
| ▸ | ATR | Q13535 | 3/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488736 | 1.00 | TYRO3 (0.42) | TYRO3CSF1RPIK3CDPIK3CAPIK3CG | |
| SCHEMBL30453160 | 0.91 | CSF1R (0.37) | CSF1RPIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL487878 | 0.91 | CSF1R (0.37) | CSF1RPIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL30453889 | 0.89 | TYRO3 (0.42) | TYRO3CSF1RPIK3CDPIK3CAPIK3CG | |
| SCHEMBL488496 | 0.89 | TYRO3 (0.42) | TYRO3CSF1RPIK3CDPIK3CAPIK3CG | |
| SCHEMBL488372 | 0.86 | MET (0.44) | TYRO3CCNT1MAP4K4 | |
| SCHEMBL30452886 | 0.86 | MET (0.44) | TYRO3CCNT1MAP4K4 | |
| SCHEMBL488554 | 0.85 | TYRO3 (0.40) | TYRO3CSF1RPIK3CDPIK3CAPIK3CG | |
| SCHEMBL30452628 | 0.85 | TYRO3 (0.40) | TYRO3CSF1RPIK3CDPIK3CAPIK3CG | |
| SCHEMBL488225 | 0.85 | TYRO3 (0.42) | TYRO3CSF1RPIK3CDPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |