Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.44 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488372 | 1.00 | MET (0.44) | METMAP4K3JAK2ACVR1FYN | |
| SCHEMBL30452927 | 0.91 | MET (0.49) | METMAP4K3JAK2FYNRIPK2 | |
| SCHEMBL488262 | 0.91 | MET (0.49) | METMAP4K3JAK2FYNRIPK2 | |
| SCHEMBL487979 | 0.89 | MET (0.45) | METMAP4K3JAK2ACVR1FYN | |
| SCHEMBL30453826 | 0.89 | MET (0.45) | METMAP4K3JAK2ACVR1FYN | |
| SCHEMBL488736 | 0.86 | TYRO3 (0.42) | TYRO3MAP4K4CCNT1 | |
| SCHEMBL30452783 | 0.86 | TYRO3 (0.42) | TYRO3MAP4K4CCNT1 | |
| SCHEMBL487812 | 0.85 | MET (0.41) | METMAP4K3JAK2ACVR1FYN | |
| SCHEMBL30453720 | 0.85 | MET (0.41) | METMAP4K3JAK2ACVR1FYN | |
| SCHEMBL488343 | 0.84 | MET (0.51) | METMAP4K3JAK2ACVR1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |