Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.61 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.61 |
| ▸ | ATR | Q13535 | 5/20 | 0.57 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 3/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.42 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.42 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.41 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488582 | 1.00 | MET (0.61) | METCHEK2ATRCSF1RJAK1 | |
| SCHEMBL488743 | 0.93 | ATR (0.59) | METCHEK2ATRMAP4K3ACVR1 | |
| SCHEMBL30453739 | 0.93 | ATR (0.59) | METCHEK2ATRMAP4K3ACVR1 | |
| SCHEMBL30452777 | 0.90 | MET (0.60) | METCHEK2ATRMAP4K3 | |
| SCHEMBL488291 | 0.90 | MET (0.60) | METCHEK2ATRMAP4K3 | |
| SCHEMBL488073 | 0.88 | MET (0.54) | METCHEK2ATRMAP4K3 | |
| SCHEMBL30454532 | 0.88 | MET (0.54) | METCHEK2ATRMAP4K3 | |
| SCHEMBL30452481 | 0.85 | MET (0.59) | METCHEK2ATRMAP4K3 | |
| SCHEMBL487858 | 0.85 | MET (0.59) | METCHEK2ATRMAP4K3 | |
| SCHEMBL30453481 | 0.84 | MET (0.60) | METATRACVR1BMPR1BBMPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |