Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 5/20 | 0.59 |
| ▸ | MET | P08581 | 4/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.53 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | MERTK | Q12866 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 2/20 | 0.46 |
| ▸ | LDHB | P07195 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.40 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.40 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488743 | 1.00 | ATR (0.59) | ATRMETCHEK2AXLMERTK | |
| SCHEMBL488582 | 0.93 | MET (0.61) | ATRMETCHEK2MAP4K3BMPR1B | |
| SCHEMBL30452827 | 0.93 | MET (0.61) | ATRMETCHEK2MAP4K3BMPR1B | |
| SCHEMBL487858 | 0.92 | MET (0.59) | ATRMETCHEK2AXLMERTK | |
| SCHEMBL30452481 | 0.92 | MET (0.59) | ATRMETCHEK2AXLMERTK | |
| SCHEMBL30454131 | 0.90 | ATR (0.56) | ATRMETCHEK2AXLMERTK | |
| SCHEMBL488250 | 0.90 | ATR (0.56) | ATRMETCHEK2AXLMERTK | |
| SCHEMBL30453654 | 0.86 | MET (0.54) | ATRMETAXLMERTKBMPR1B | |
| SCHEMBL487905 | 0.86 | MET (0.54) | ATRMETAXLMERTKBMPR1B | |
| SCHEMBL489049 | 0.84 | ATR (0.55) | ATRMETCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |