SCHEMBL30452836

SCHEMBL30452836

Nc1ncc(-c2cccc(C(=O)N3CCC[C@@H]3CN3CCCC3)c2)cc1OCc1c(Cl)cccc1Cl

nearest known ligand 0.86

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MET P08581 15/20 0.86
CSF1R P07333 2/20 0.65
ALK Q9UM73 2/20 0.53
ATR Q13535 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10316972 1.00 MET (0.86) METCSF1RALKATR
SCHEMBL487625 1.00 MET (0.86) METCSF1RALKATR
SCHEMBL489386 0.93 MET (1.00) METCSF1RALKATR
SCHEMBL30453496 0.93 MET (1.00) METCSF1RALKATR
SCHEMBL487952 0.93 MET (1.00) METCSF1RALKATR
SCHEMBL30452772 0.93 MET (1.00) METCSF1RALKATR
SCHEMBL487623 0.93 MET (1.00) METCSF1RALKATR
SCHEMBL6363660 0.92 MET (0.74) METCSF1RALKATR
SCHEMBL487656 0.90 MET (0.84) METCSF1RALKATR
SCHEMBL30452972 0.90 MET (0.84) METCSF1RALKATR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113181362-B Medicament for preventing and/or treating amyotrophic lateral sclerosis 国立大学法人京都大学 2023-06-13 CN disclosed