Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.50 |
| ▸ | HPGDS | O60760 | 3/20 | 0.49 |
| ▸ | ATR | Q13535 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488001 | 1.00 | CD274 (0.50) | CD274HPGDSATRHPGDMAP4K4 | |
| SCHEMBL10216349 | 0.93 | MAP4K4 (0.52) | CD274HPGDSATRHPGDMAP4K4 | |
| SCHEMBL5482536 | 0.86 | CD274 (0.53) | CD274HPGDSHPGDMAP4K4EPHX2 | |
| SCHEMBL488293 | 0.83 | ATR (0.48) | ATRMAP4K4 | |
| SCHEMBL488441 | 0.82 | ATR (0.51) | ATRHPGDMAP4K4MAPT | |
| SCHEMBL30454216 | 0.82 | ATR (0.51) | ATRHPGDMAP4K4MAPT | |
| SCHEMBL30453653 | 0.82 | ATR (0.54) | ATR | |
| SCHEMBL487938 | 0.82 | ATR (0.54) | ATR | |
| SCHEMBL30453023 | 0.82 | CD274 (0.50) | CD274HPGDSATRHPGDMAP4K4 | |
| SCHEMBL488479 | 0.82 | CD274 (0.50) | CD274HPGDSATRHPGDMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |