Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 11/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | ATR | Q13535 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488479 | 1.00 | CD274 (0.50) | CD274HPGDSALDH1A1HTR1AMAOA | |
| SCHEMBL488475 | 0.95 | KLK7 (0.47) | CD274HPGDSALDH1A1HTR1AMAOA | |
| SCHEMBL30454451 | 0.95 | KLK7 (0.47) | CD274HPGDSALDH1A1HTR1AMAOA | |
| SCHEMBL487751 | 0.93 | ATR (0.55) | ALDH1A1METATRMAP4K4 | |
| SCHEMBL30453304 | 0.93 | ATR (0.55) | ALDH1A1METATRMAP4K4 | |
| SCHEMBL30453395 | 0.92 | MAP4K4 (0.54) | CD274HPGDSALDH1A1HTR1AMAOA | |
| SCHEMBL488692 | 0.92 | MAP4K4 (0.54) | CD274HPGDSALDH1A1HTR1AMAOA | |
| SCHEMBL488316 | 0.89 | MET (0.48) | CD274METATR | |
| SCHEMBL30453094 | 0.88 | ATR (0.50) | ALDH1A1METATR | |
| SCHEMBL488513 | 0.88 | ATR (0.50) | ALDH1A1METATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |