Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 5/20 | 0.54 |
| ▸ | PTK2 | Q05397 | 6/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487938 | 1.00 | ATR (0.54) | ATRPTK2SLC6A5HDAC4HDAC6 | |
| SCHEMBL488735 | 0.85 | MET (0.49) | ATRPTK2SLC6A5HDAC4HDAC6 | |
| SCHEMBL30454046 | 0.85 | MET (0.49) | ATRPTK2SLC6A5HDAC4HDAC6 | |
| SCHEMBL488626 | 0.85 | KCNH2 (0.56) | ATRKCNH2 | |
| SCHEMBL30454874 | 0.85 | KCNH2 (0.56) | ATRKCNH2 | |
| SCHEMBL30452854 | 0.82 | CD274 (0.50) | ATR | |
| SCHEMBL488001 | 0.82 | CD274 (0.50) | ATR | |
| SCHEMBL30453567 | 0.81 | ATR (0.55) | ATRSLC6A5HDAC4HDAC6CHEK2 | |
| SCHEMBL488430 | 0.81 | ATR (0.55) | ATRSLC6A5HDAC4HDAC6CHEK2 | |
| SCHEMBL488522 | 0.81 | MAP4K4 (0.43) | ATRKCNH2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |