SCHEMBL30452877

SCHEMBL30452877

CC(Oc1cc(-c2cccc(C(=O)NCCCN3CCOCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl

nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MET P08581 12/20 0.69
ALK Q9UM73 8/20 0.62
JAK2 O60674 2/20 0.54
AXL P30530 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL488655 1.00 MET (0.69) METALKJAK2AXL
SCHEMBL30453721 0.96 MET (0.75) METALKJAK2AXL
SCHEMBL487746 0.96 MET (0.75) METALKJAK2AXL
SCHEMBL30452930 0.94 MET (0.78) METALKJAK2AXL
SCHEMBL488563 0.94 MET (0.78) METALKJAK2AXL
SCHEMBL10216455 0.92 MET (0.80) METALKJAK2AXL
SCHEMBL30453756 0.92 MET (0.68) METALKJAK2
SCHEMBL488589 0.92 MET (0.68) METALKJAK2
SCHEMBL487752 0.90 MET (0.85) METALKJAK2AXL
SCHEMBL30453645 0.90 MET (0.85) METALKJAK2AXL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113181362-B Medicament for preventing and/or treating amyotrophic lateral sclerosis 国立大学法人京都大学 2023-06-13 CN disclosed