Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.68 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.58 |
| ▸ | GRK5 | P34947 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488589 | 1.00 | MET (0.68) | METALKGRK5MAP4K4JAK2 | |
| SCHEMBL30453721 | 0.96 | MET (0.75) | METALKJAK2 | |
| SCHEMBL487746 | 0.96 | MET (0.75) | METALKJAK2 | |
| SCHEMBL30454143 | 0.94 | MET (0.77) | METALKJAK2 | |
| SCHEMBL488639 | 0.94 | MET (0.77) | METALKJAK2 | |
| SCHEMBL30452627 | 0.92 | MET (0.80) | METALKJAK2 | |
| SCHEMBL488578 | 0.92 | MET (0.80) | METALKJAK2 | |
| SCHEMBL488655 | 0.92 | MET (0.69) | METALKJAK2 | |
| SCHEMBL30452877 | 0.92 | MET (0.69) | METALKJAK2 | |
| SCHEMBL30453726 | 0.90 | MET (0.62) | METALKGRK5MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |