Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 4/20 | 0.35 |
| ▸ | SGK1 | O00141 | 8/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SGK3 | Q96BR1 | 1/20 | 0.34 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487823 | 1.00 | CSF1R (0.37) | CSF1RMETSGK1PIK3CDPIK3CA | |
| SCHEMBL488496 | 0.91 | TYRO3 (0.42) | CSF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30453889 | 0.91 | TYRO3 (0.42) | CSF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30453160 | 0.89 | CSF1R (0.37) | CSF1RMETSGK1PIK3CDPIK3CA | |
| SCHEMBL487878 | 0.89 | CSF1R (0.37) | CSF1RMETSGK1PIK3CDPIK3CA | |
| SCHEMBL30453744 | 0.85 | MET (0.50) | METMAP4K3 | |
| SCHEMBL487916 | 0.85 | MET (0.50) | METMAP4K3 | |
| SCHEMBL488492 | 0.85 | MAP4K3 (0.46) | METSGK1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30453976 | 0.85 | MAP4K3 (0.46) | METSGK1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL488100 | 0.84 | CSF1R (0.41) | CSF1RMETSGK1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |