Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.65 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488185 | 1.00 | MET (0.65) | METMAP4K3MAP4K4KCNH2 | |
| SCHEMBL14631924 | 0.90 | MET (0.66) | METMAP4K3MAP4K4KCNH2 | |
| SCHEMBL30453547 | 0.90 | MET (0.66) | METMAP4K3MAP4K4KCNH2 | |
| SCHEMBL488202 | 0.90 | MET (0.66) | METMAP4K3MAP4K4KCNH2 | |
| SCHEMBL30453454 | 0.90 | MET (0.56) | METMAP4K3MAP4K4KCNH2 | |
| SCHEMBL488399 | 0.90 | MET (0.56) | METMAP4K3MAP4K4KCNH2 | |
| SCHEMBL30454310 | 0.88 | MET (0.62) | METMAP4K3MAP4K4 | |
| SCHEMBL487914 | 0.88 | MET (0.62) | METMAP4K3MAP4K4 | |
| SCHEMBL488476 | 0.88 | MET (0.68) | METMAP4K4KCNH2 | |
| SCHEMBL30453219 | 0.88 | MET (0.68) | METMAP4K4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |