Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.37 |
| ▸ | MET | P08581 | 4/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488448 | 1.00 | CSF1R (0.37) | CSF1RMETTLR7S1PR1L3MBTL1 | |
| SCHEMBL10216305 | 1.00 | CSF1R (0.37) | CSF1RMETTLR7S1PR1L3MBTL1 | |
| SCHEMBL30453085 | 0.88 | S1PR1 (0.41) | CSF1RMETS1PR1DRD4KDM4E | |
| SCHEMBL488054 | 0.88 | S1PR1 (0.41) | CSF1RMETS1PR1DRD4KDM4E | |
| SCHEMBL10215218 | 0.87 | MET (0.45) | METTLR7S1PR1DRD4KDM4E | |
| SCHEMBL488169 | 0.87 | MET (0.45) | METTLR7S1PR1DRD4KDM4E | |
| SCHEMBL488507 | 0.87 | LRRK2 (0.41) | CSF1RMETS1PR1DRD4LRRK2 | |
| SCHEMBL30453800 | 0.87 | LRRK2 (0.41) | CSF1RMETS1PR1DRD4LRRK2 | |
| SCHEMBL488471 | 0.87 | S1PR1 (0.41) | CSF1RMETS1PR1KDM4EICMT | |
| SCHEMBL30453674 | 0.87 | S1PR1 (0.41) | CSF1RMETS1PR1KDM4EICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |