Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 4/20 | 0.40 |
| ▸ | CSF1R | P07333 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 3/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488471 | 1.00 | S1PR1 (0.41) | S1PR1METCSF1RLMNAHTT | |
| SCHEMBL488054 | 0.99 | S1PR1 (0.41) | S1PR1METCSF1RLMNAHTT | |
| SCHEMBL30453085 | 0.99 | S1PR1 (0.41) | S1PR1METCSF1RLMNAHTT | |
| SCHEMBL30453800 | 0.92 | LRRK2 (0.41) | S1PR1METCSF1RJAK2MPO | |
| SCHEMBL488507 | 0.92 | LRRK2 (0.41) | S1PR1METCSF1RJAK2MPO | |
| SCHEMBL30453537 | 0.89 | MET (0.40) | S1PR1METCSF1RLMNAHTT | |
| SCHEMBL487928 | 0.89 | MET (0.40) | S1PR1METCSF1RLMNAHTT | |
| SCHEMBL488448 | 0.87 | CSF1R (0.37) | S1PR1METCSF1RKDM4EJAK2 | |
| SCHEMBL30453037 | 0.87 | CSF1R (0.37) | S1PR1METCSF1RKDM4EJAK2 | |
| SCHEMBL10216305 | 0.87 | CSF1R (0.37) | S1PR1METCSF1RKDM4EJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |