Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.62 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488192 | 1.00 | MET (0.62) | METCD274HPGDLMNARAB9A | |
| SCHEMBL488212 | 0.95 | MET (0.60) | METCD274LMNARAB9A | |
| SCHEMBL30454062 | 0.95 | MET (0.60) | METCD274LMNARAB9A | |
| SCHEMBL488567 | 0.91 | MET (0.61) | METCD274HPGDHPGDS | |
| SCHEMBL30454986 | 0.91 | MET (0.61) | METCD274HPGDHPGDS | |
| SCHEMBL487776 | 0.87 | MET (0.56) | METCD274HPGDHPGDS | |
| SCHEMBL30452829 | 0.87 | MET (0.56) | METCD274HPGDHPGDS | |
| SCHEMBL30452926 | 0.86 | MET (0.56) | METCD274 | |
| SCHEMBL487849 | 0.86 | MET (0.56) | METCD274 | |
| SCHEMBL488424 | 0.86 | CD274 (0.58) | METCD274HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |