Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 10/20 | 0.57 |
| ▸ | JAK2 | O60674 | 5/20 | 0.53 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487861 | 1.00 | MET (0.57) | METJAK2MAP4K3MAP4K4ALK | |
| SCHEMBL487622 | 0.90 | MET (0.52) | METJAK2MAP4K3MAP4K4FYN | |
| SCHEMBL487679 | 0.88 | MET (0.57) | METJAK2MAP4K3MAP4K4ALK | |
| SCHEMBL488145 | 0.87 | MET (0.68) | METJAK2MAP4K3MAP4K4 | |
| SCHEMBL488409 | 0.86 | MET (0.48) | METJAK2MAP4K3MAP4K4FYN | |
| SCHEMBL487796 | 0.85 | MET (0.57) | METJAK2MAP4K3MAP4K4FYN | |
| SCHEMBL487559 | 0.84 | MET (0.53) | METJAK2MAP4K3MAP4K4ALK | |
| Water SCHEMBL28122580 | 0.84 | MET (0.56) | METJAK2MAP4K3MAP4K4FYN | |
| SCHEMBL487907 | 0.82 | MET (0.81) | METJAK2MAP4K3MAP4K4FYN | |
| SCHEMBL21844366 | 0.81 | MET (0.43) | METJAK2MAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |