SCHEMBL3045330

SCHEMBL3045330

C=CC(=O)OCCc1cccc(C(=O)OCCO)c1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.46
THRB P10828 1/20 0.44
ALDH1A1 P00352 6/20 0.36
TP53 P04637 3/20 0.36
HIF1A Q16665 3/20 0.36
HSD17B10 Q99714 3/20 0.36
CYP3A4 P08684 3/20 0.36
NPC1 O15118 2/20 0.36
HPGD P15428 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
GLA P06280 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
FOLH1 Q04609 3/20 0.36
HCAR2 Q8TDS4 1/20 0.35
SCN1A P35498 2/20 0.34
SCN2A Q99250 2/20 0.34
SCN3A Q9NY46 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5479977 0.93 THRB (0.46) TSHRTHRBALDH1A1TP53HIF1A
SCHEMBL57853 0.87 THRB (0.50) TSHRTHRBALDH1A1TP53HIF1A
SCHEMBL29612237 0.87 THRB (0.50) TSHRTHRBALDH1A1TP53HIF1A
Triethylene Glycol SCHEMBL28273454 0.87 ALDH1A1 (0.45) TSHRTHRBALDH1A1TP53HIF1A
SCHEMBL29679078 0.85 THRB (0.42) TSHRTHRBALDH1A1TP53HIF1A
SCHEMBL15302409 0.85 THRB (0.44) TSHRTHRBALDH1A1TP53HIF1A
SCHEMBL28851562 0.84 THRB (0.47) TSHRTHRBALDH1A1TP53HIF1A
SCHEMBL29695333 0.83 THRB (0.42) TSHRTHRBALDH1A1TP53HIF1A
SCHEMBL3319113 0.83 THRB (0.42) TSHRTHRBALDH1A1TP53HIF1A
SCHEMBL19210181 0.83 THRB (0.51) TSHRTHRBALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1923703-B1 A method for producing a biosensor having a covalently bound thin polymeric coat FUJIFILM CORP (JP) 2015-05-06 EP disclosed
US-20150024392-A1 METHOD FOR PRODUCING A BIOSENSOR FUJIFILM CORPORATION (JP) 2015-01-22 US disclosed
US-8839961-B2 Method for producing a biosensor FUJIFILM CORPORATION (JP) 2014-09-23 US disclosed
US-8585972-B2 Biosensor FUJIFILM CORPORATION (JP) 2013-11-19 US disclosed
EP-1790984-B1 A method for producing a biosensor having a covalently bound thin polymeric coat FUJIFILM CORP (JP) 2013-08-28 EP disclosed
US-20100310882-A1 TOPCOAT MIDORI HOKUYO CO., LTD. (JP) 2010-12-09 US disclosed
US-20100221845-A1 BIOSENSOR FUJIFILM CORPORATION (JP) 2010-09-02 US disclosed
EP-1696235-B1 Biosensor FUJIFILM CORP (JP) 2009-10-28 EP disclosed
US-7563623-B2 Biosensor FUJIFILM CORPORATION (JP) 2009-07-21 US disclosed
EP-1923703-A2 A method for producing a biosensor having a covalently bound thin polymeric coat FUJIFILM Corporation (JP) 2008-05-21 EP disclosed
US-20080038841-A1 nonspecific adsorption is less likely; a large amount of protein can be immobilized by having a hydrogel (polysaccharide) bind to biosensor via a SAM (self-assembled monolayer) compound (aminoalkanethiol) having high water solubility and good performance in terms of supply; surface plasmon resonance FUJIFILM CORPORATION (JP) 2008-02-14 US disclosed
US-20070258866-A1 Method for producing a biosensor FUJIFILM CORPORATION 2007-11-08 US disclosed
EP-1826563-A1 Biosensor Fujifilm Corporation (JP) 2007-08-29 EP disclosed
EP-1790984-A2 A method for producing a biosensor having a covalently bound thin polymeric coat Fujifilm Corporation (JP) 2007-05-30 EP disclosed
US-20060240478-A1 Biosensor FUJI PHOTO FILM CO., LTD. 2006-10-26 US disclosed
EP-1696235-A1 Biosensor FUJI PHOTO FILM CO., LTD. (JP) 2006-08-30 EP disclosed