Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.56 |
| ▸ | MERTK | Q12866 | 5/20 | 0.45 |
| ▸ | AXL | P30530 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.40 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488311 | 1.00 | MET (0.56) | METMERTKAXLKDM4EALDH1A1 | |
| SCHEMBL488312 | 0.85 | MET (0.58) | METMERTKAXLKDM4EALDH1A1 | |
| SCHEMBL5255609 | 0.83 | MET (0.70) | METMERTKAXLL3MBTL3L3MBTL1 | |
| SCHEMBL30453810 | 0.81 | MET (0.55) | METMERTKAXLL3MBTL3L3MBTL1 | |
| SCHEMBL487976 | 0.81 | MET (0.55) | METMERTKAXLL3MBTL3L3MBTL1 | |
| SCHEMBL488874 | 0.81 | MET (0.61) | METMERTKAXLATR | |
| SCHEMBL30452853 | 0.81 | MET (0.61) | METMERTKAXLATR | |
| SCHEMBL488661 | 0.79 | MET (0.65) | METMERTKAXLL3MBTL3L3MBTL1 | |
| SCHEMBL30453983 | 0.79 | MET (0.65) | METMERTKAXLL3MBTL3L3MBTL1 | |
| SCHEMBL10217566 | 0.78 | MET (0.61) | METMERTKAXLKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |