Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.61 |
| ▸ | MERTK | Q12866 | 4/20 | 0.45 |
| ▸ | AXL | P30530 | 3/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488874 | 1.00 | MET (0.61) | METMERTKAXLJAK2HRH3 | |
| SCHEMBL487976 | 0.89 | MET (0.55) | METMERTKAXLATR | |
| SCHEMBL30453810 | 0.89 | MET (0.55) | METMERTKAXLATR | |
| SCHEMBL488875 | 0.85 | MET (0.62) | METMERTKAXLATR | |
| SCHEMBL5258519 | 0.84 | MET (0.61) | METMERTKAXLATR | |
| SCHEMBL30453096 | 0.84 | MET (0.54) | METMERTKAXLATR | |
| SCHEMBL488368 | 0.84 | MET (0.54) | METMERTKAXLATR | |
| SCHEMBL487881 | 0.83 | MET (0.81) | METMERTKAXLJAK2ATR | |
| SCHEMBL30453513 | 0.83 | MET (0.81) | METMERTKAXLJAK2ATR | |
| SCHEMBL5255609 | 0.81 | MET (0.70) | METMERTKAXLJAK2ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |