Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.65 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488532 | 1.00 | MET (0.65) | METMAP4K3KCNH2MAP4K4PIK3CD | |
| SCHEMBL30453650 | 0.93 | MET (0.65) | METMAP4K3KCNH2MAP4K4 | |
| SCHEMBL488012 | 0.93 | MET (0.65) | METMAP4K3KCNH2MAP4K4 | |
| SCHEMBL6364339 | 0.91 | MET (0.55) | METMAP4K3KCNH2PIK3CDPIK3CA | |
| SCHEMBL27915639 | 0.89 | MET (0.61) | METMAP4K3KCNH2MAP4K4ALDH1A1 | |
| SCHEMBL27915640 | 0.88 | MET (0.60) | METMAP4K3KCNH2MAP4K4ALDH1A1 | |
| SCHEMBL488146 | 0.86 | MET (0.63) | METMAP4K3KCNH2MAP4K4 | |
| SCHEMBL30453233 | 0.86 | MET (0.63) | METMAP4K3KCNH2MAP4K4 | |
| SCHEMBL30453248 | 0.86 | MET (0.69) | METMAP4K3MAP4K4 | |
| SCHEMBL487635 | 0.86 | MET (0.69) | METMAP4K3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |