Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.59 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.51 |
| ▸ | NEK2 | P51955 | 5/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.47 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.47 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488012 | 1.00 | MET (0.65) | METKCNH2MAP4K3NEK2MAP4K4 | |
| SCHEMBL488532 | 0.93 | MET (0.65) | METKCNH2MAP4K3MAP4K4 | |
| SCHEMBL30453327 | 0.93 | MET (0.65) | METKCNH2MAP4K3MAP4K4 | |
| SCHEMBL27915639 | 0.89 | MET (0.61) | METKCNH2MAP4K3NEK2MAP4K4 | |
| SCHEMBL27915640 | 0.88 | MET (0.60) | METKCNH2MAP4K3NEK2MAP4K4 | |
| SCHEMBL30454652 | 0.87 | KCNH2 (0.56) | METKCNH2MAP4K4BMPR1BBMPR1A | |
| SCHEMBL488288 | 0.87 | KCNH2 (0.56) | METKCNH2MAP4K4BMPR1BBMPR1A | |
| SCHEMBL30453079 | 0.86 | MET (0.63) | METKCNH2MAP4K3MAP4K4BMPR1B | |
| SCHEMBL488445 | 0.86 | MET (0.63) | METKCNH2MAP4K3MAP4K4BMPR1B | |
| SCHEMBL30453248 | 0.86 | MET (0.69) | METMAP4K3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |