Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.68 |
| ▸ | ATR | Q13535 | 6/20 | 0.54 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488463 | 1.00 | MET (0.68) | METATRMAP4K3CHEK2MAP4K4 | |
| SCHEMBL30453330 | 0.96 | MET (0.62) | METATRMAP4K3CHEK2MAP4K4 | |
| SCHEMBL488485 | 0.96 | MET (0.62) | METATRMAP4K3CHEK2MAP4K4 | |
| SCHEMBL488531 | 0.96 | MET (0.61) | METATRMAP4K3CHEK2MAP4K4 | |
| SCHEMBL30453089 | 0.96 | MET (0.61) | METATRMAP4K3CHEK2MAP4K4 | |
| SCHEMBL30452825 | 0.94 | MET (0.60) | METATRMAP4K3CHEK2MAP4K4 | |
| SCHEMBL487974 | 0.94 | MET (0.60) | METATRMAP4K3CHEK2MAP4K4 | |
| SCHEMBL488055 | 0.93 | MET (0.59) | METATRMAP4K3CHEK2MAP4K4 | |
| SCHEMBL30453791 | 0.92 | ATR (0.59) | METATRCHEK2MAP4K4IKBKB | |
| SCHEMBL488359 | 0.92 | ATR (0.59) | METATRCHEK2MAP4K4IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |