Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 7/20 | 0.59 |
| ▸ | MET | P08581 | 5/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488359 | 1.00 | ATR (0.59) | ATRMETCHEK2MAP4K4IKBKB | |
| SCHEMBL30452733 | 0.95 | MET (0.55) | ATRMETCHEK2MAP4K4IKBKB | |
| SCHEMBL488699 | 0.95 | MET (0.55) | ATRMETCHEK2MAP4K4IKBKB | |
| SCHEMBL488889 | 0.93 | MAP4K4 (0.54) | ATRMETCHEK2MAP4K4ADORA2A | |
| SCHEMBL30454081 | 0.93 | MAP4K4 (0.54) | ATRMETCHEK2MAP4K4ADORA2A | |
| SCHEMBL488319 | 0.93 | MET (0.65) | ATRMETCHEK2MAP4K4IKBKB | |
| SCHEMBL30453897 | 0.93 | MET (0.65) | ATRMETCHEK2MAP4K4IKBKB | |
| SCHEMBL488242 | 0.92 | MET (0.52) | ATRMETCHEK2MAP4K4IKBKB | |
| SCHEMBL30453345 | 0.92 | MET (0.68) | ATRMETCHEK2MAP4K4IKBKB | |
| SCHEMBL488463 | 0.92 | MET (0.68) | ATRMETCHEK2MAP4K4IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |