SCHEMBL30453381

SCHEMBL30453381

CN(CC(O)CN1CCCC1)C(=O)c1ccc(-c2cnc(N)c(OCc3c(Cl)cccc3Cl)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MET P08581 17/20 0.59
CSF1R P07333 1/20 0.42
MAP4K4 O95819 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL488193 1.00 MET (0.59) METCSF1RMAP4K4
SCHEMBL487541 0.84 MET (0.60) METCSF1RMAP4K4
SCHEMBL30454277 0.84 MET (0.60) METCSF1RMAP4K4
SCHEMBL30453780 0.75 MET (0.76) METMAP4K4
SCHEMBL487674 0.75 MET (0.76) METMAP4K4
SCHEMBL488098 0.74 MET (0.63) METMAP4K4
SCHEMBL30453146 0.74 MET (0.63) METMAP4K4
SCHEMBL487623 0.74 MET (1.00) METCSF1R
SCHEMBL489386 0.74 MET (1.00) METCSF1R
SCHEMBL487952 0.74 MET (1.00) METCSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113181362-B Medicament for preventing and/or treating amyotrophic lateral sclerosis 国立大学法人京都大学 2023-06-13 CN disclosed